Membrane damage and interleukin-1 production in murine macrophages exposed to listeriolysin O

H Yoshikawa, I Kawamura, M Fujita, H Tsukada, M Arakawa, M Mitsuyama
1993 Infection and Immunity  
To obtain some insight into the interaction between listeriolysin 0 (LLO) and the macrophage membrane, we examined the effect of purified Listeria monocytogenes hemolysin on the viability and functions of mouse peritoneal exudate macrophages. The study showed that purified LLO impaired a variety of functions of the
doi:10.1128/iai.61.4.1334-1339.1993 fatcat:t7kdemdyrzd7hnqbgf7moxrvli