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Inspired by the biological vaccines, we explore the possibility of developing similar vaccines for malware immunization. We provide the first systematic study towards this direction and present a prototype system, AGAMI, for automatic generation of vaccines for malware immunization. With a novel use of several dynamic malware analysis techniques, we show that it is possible to extract a lightweight vaccine from current malware, and after injecting such vaccine on clean machines, they can bedoi:10.1145/2382196.2382317 dblp:conf/ccs/XuZGL12 fatcat:evihnfpd2jas5ot73qtdr45ina