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The present study is focused on the preliminary phytochemical and antibacterial evaluation of leaves of an important medicinal plant Croton bonplandianum (Euphorbiaceae). The aqueous and methanolic extracts of powdered drugs of leaves of the plants were analyzed phytochemically. Alkaloids, phenolics, flavonoids, anthraquinones, coumarins and glycosides were present while tannins were absent in all extracts. Aqueous extracts of leaves showed moderate antibacterial activity against all testedfatcat:xsq23hzbozcslgeprunqzbiyva