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Mortality of lead smelter workers with the glucose-6-phosphate dehydrogenase-deficient phenotype
Cancer Epidemiology, Biomarkers and Prevention
The mortality experience of 1345 male workers in a lead and zinc smelting plant was followed from 1973 to 1991. Information on the erythrocyte glucose-6-phosphate dehydrogenase (G6PD) phenotype was available for 1,222 (90.9%) cohort members, which provided the opportunity to compare the mortality experience of G6PD-deficient subjects to wild-type-G6PD coworkers with similar exposure to lead. A significant decrease in mortality was observed among the total cohort as well as among the subcohortpmid:8833623 fatcat:i2bpvrthxzcwnid73cd5b7wy4y