The ferredoxin/thioredoxin system: from discovery to molecular structures and beyond [chapter]

Bob B. Buchanan1, P. Schürmann, Ricardo A. Wolosiuk, Jean-Pierre Jacquot
Discoveries in Photosynthesis  
Experiments initiated in the early 1960s on fermentative bacteria led to the discovery of ferredoxin-dependent alpha-ketocarboxylation reactions that were later found to be key to a new cycle for the assimilation of carbon dioxide in photosynthetic bacteria (the reductive carboxylic acid or reverse citric cycle). The latter finding set the stage for the discovery of a regulatory system, the ferredoxin/thioredoxin system, functional in photosynthesis in chloroplasts and oxygen-evolving
more » ... etic prokaryotes. The chloroplast research led to a description of the extraplastidic NADP/thioredoxin system that is now known to function in heterotrophic plant processes such as seed germination and self-incompatibility. Extensions of the fundamental research have begun to open doors to the broad application of thioredoxin in technology and medicine.
doi:10.1007/1-4020-3324-9_76 fatcat:3r5n6yrfvzf53jibvvzfr453pa