Subcutaneous phaeohyphomycosis caused by Exophiala equina, with susceptibility to eight antifungal drugs

M. J. Najafzadeh, M. K. Suh, M. H. Lee, G. Y. Ha, J. R. Kim, T. H. Kim, H. J. Lee, J. S. Choi, J. F. Meis, G. S. De Hoog
2013 Journal of Medical Microbiology  
A case of subcutaneous phaeohyphomycosis caused by Exophiala equina is reported in a 75year-old female, who showed subcutaneous abscesses on both forearms for 8 months. A lesion was initiated by inoculation with a spine from a tree. Histopathologically, suppurative granulomatous inflammation was present and short hyphal elements were observed. Upon culture greyish-black, velvety colonies of a black yeast were obtained after 3 weeks. The strain grew well at 25 6C, but poorly at 37 6C. After
more » ... ncing the internal transcribed spacer domain and the partial b-tubulin gene, the fungus was identified as E. equina. The patient was successfully treated with fluconazole for 3 months. The GenBank/EMBL/DDBJ accession numbers for the ITS and BT2 sequences of the E. equina isolate are JQ797584 and JQ797585, respectively.
doi:10.1099/jmm.0.057406-0 pmid:23449873 fatcat:lix75rohcbetjp7yghjuaietie