We explore the phase diagram of two-flavor QCD at imaginary values of baryon and isospin chemical potentials analyzing the thermodynamic potential of QCD analytically and that of the Polyakov-loop extended Nambu-Jona-Lasinio (PNJL) model numerically. QCD has no pion condensation at imaginary baryon and isospin chemical potentials, and therefore has discrete symmetries that are not present at real baryon and isospin chemical potentials. The PNJL model possesses all the discrete symmetries. The

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... JL model can reproduce qualitatively lattice QCD data presented very lately.