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Escherichia coli K-12 Hfr and F-strains were successively implanted in axenic chicks. Conjugation with exchanges of chromosomal genes occurred with high frequencies in the gut of the chicks and could continue as long as fertile strains coexisted in this environment. Almost all of the expected recombinant types were recovered in the feces under these experimental conditions. Furthermore, these recombinants were analogous to those obtained after conjugations in vitro. Recombinants formed in thedoi:10.1128/aem.47.4.639-642.1984 fatcat:6s3yb7eejzg6lm7qkehq3j5zum