Serum potassium levels in Thai patients with T2DM and eGFR greater than or equal to 90 ml/min/1.73 m2

Jirayut Janma, Siribha Changsirikulchai, Pornpen Sangthawan, Nintita Sripaiboonkij Thokanit, Suthee Rattanamongkolgul, Bandit Thinkhamrop
2019 Trends in Medicine  
Disturbances in potassium levels can occur in patients with renal dysfunction. This study's aim is to describe the serum potassium (sK) levels in Thai patients with type 2 Diabetes (T2DM) with or without hypertension (HT) and with estimated glomerular filtration rates (eGFR) greater than or equal to 90 ml/ minute/1.73 m 2 . Methods: There was a cross sectional study performed throughout Thailand in 2016 for assessment on the quality of care among patients diagnosed with T2DM and HT. We selected
more » ... a subgroup of patients who had data of sK levels and eGFR value greater than or equal to 90 ml/minute/1.73 m 2 for analyses. Results: There were 3,719 subjects who met the inclusion criteria. The mean (SD) eGFR was 102.59 (9.12) ml/minute/1.73m 2 . The mean (SD)sK level was 4.11 (0.52) mEq/L. The mean (SD) SBP and DBP were 130.86 (15.47) and 76.15 (10.14) mmHg, respectively. The sK levels were categorized into 3 groups: low, normal and high at <3.5, 3.5-5.0 and >5 mEq/L, respectively. The prevalence of hypokalemia was 6.7 % and level less than 3 mEq/L was found in 55.6% of the hypokalemic population. The percentage of hypokalemia was found to be high in the group with diuretic usage. The prevalence of hyperkalemia was 2.9% and levels more than 5.5 mEq/L was found in 21.7% of the hyperkalemic group. Conclusions: The hypokalemia and hyperkalemia in T2DM with or without hypertension and eGFR≥90 ml/minute/1.73 m 2 can be found. The sK levels less than 3 mEq/L could be related to diuretic usage. Therefore, patients who are prescribed diuretics or renin angiotensin aldosterone blockades should have sK levels regularly monitored.
doi:10.15761/tim.1000178 fatcat:aqv7xpn3lbhvffokgk6duj3qem