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The role of renin-angiotensin system in prothrombotic state in essential hypertension
2009
Physiological Research
Rheological, haemostatic, endothelial and platelet abnormalities appear to play a role in the thrombotic complications of hypertension. This prothrombotic/hypercoagulable state in hypertension may contribute to the increased risk and severity of target organ damage. It can be induced by the activated renin-angiotensin system (RAS), with abnormalities in endothelial and platelet function, coagulation and fibrinolysis. Treatment of uncomplicated essential hypertension by RAS targeting
pmid:19249905
fatcat:kt2lc6j7e5dpdiiio4fc4xmqzy