Molecular characterization of human Torque Teno virus

YOUPING WEI, MINYANG CHEN, XIA YANG, LIMING ZHANG, LIHUA RAO, FEIFANG YUAN, YANGQIN WANG, JING GONG, LIANPING LI
2015 Biomedical Reports  
The present study analyzed the presence of human Torque Teno virus (TTV) in hospitalized patients from different departments. In total, 378 serum specimens were collected from the patients (171 with cardiovascular disease, 192 with tumor and 15 with gastroenteritis) and analyzed by ELISA and nest-polymerase chain reaction (PCR) to detect the presence of TTV. The results showed that 64 specimens (17%) were TTV positive from detection with the human ELISA kit, and the patients aged <30 years have
more » ... a higher prevalence. TTV in males was more common than in female patients. In addition, nest-PCR was used to detect TTV within different phylogenetic groups among the 64 specimens, and the results showed that groups 1 (TA278 strain), 4 (KC009) and 5 (CT39) were much more prevalent than groups 2 (PMV isolate) and 3 (11 genotypes) in the different departmental patients.
doi:10.3892/br.2015.508 pmid:26623023 pmcid:PMC4660652 fatcat:ogeayb4iofdelguj47u6pydomi