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Proteins in Wonderland: The Magical World of Pressure
2021
Biology
Admitting the "Native", "Unfolded" and "Fibril" states as the three basic generic states of proteins in nature, each of which is characterized with its partial molar volume, here we predict that the interconversion among these generic states N, U, F may be performed simply by making a temporal excursion into the so called "the high-pressure regime", created artificially by putting the system under sufficiently high hydrostatic pressure, where we convert N to U and F to U, and then back to "the
doi:10.3390/biology11010006
pmid:35053003
pmcid:PMC8772990
fatcat:z5p7fufqrzbd7jvwumjdzalmei