Malignant Lymphoma Demonstrating Sick Sinus Syndrome

Mitsuhiro KAMIMURA, Noriko TANABE, Masaaki HOJO, Tadashi HORIUCHI, Koichiro KUDO, Kiyoshi SAITOH
1998 Internal medicine (Tokyo. 1992)  
ereport a case of T-cell-rich large B-cell lymphomademonstrating sick sinus syndrome as a single initial symptom, followed by the retention ofpericardial and pleural effusions. Intrapleural administration of interferon-a prevented reaccumulation of the pleural effusion for one and a half months, whereas systemic chemotherapy failed to control tumor growth in the skin and lymph nodes. The autopsy revealed involvement of the sinoatrial node of the heart by lymphomacells.
doi:10.2169/internalmedicine.37.463 fatcat:d7ufftvzivgxvfcp5h2nkf2aqy