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beta-Catenin/Tcf-regulated transcription prior to the midblastula transition
2002
Development
Following fertilization, the zygotic genome in many organisms is quiescent until the midblastula transition (MBT), when large-scale transcription begins. In Xenopus embryos, for example, transcription is believed to be repressed until the twelfth cell division. Thus, although dorsal-ventral patterning begins during the first cell cycle, little attention has been given to transcriptional regulation in pre-MBT development. We present evidence that regulated transcription begins during early
doi:10.1242/dev.00150
pmid:12421713
fatcat:pvpsbqvyljhz5erxznmr6jnvsy