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ASSAY IN MICE FOR MINUTE AMOUNTS OF ENDOTOXIN BY PRE-ADMINISTRATION OF LEAD ACETATE
1982
Japanese Journal of Medical Science & Biology
The enhancing effect of pre-administration of lead acetate on the body-weight decrease due to endotoxin was studied in mice for the purpose of developing a method for determination of minute amounts of endotoxin. By adoption of the body-weight ratio on the first day after endotoxin administration (BWR1) as a response, the linear regression lines of the dose-response were demonstrated over a wide range of log doses of several different endotoxin preparations tested. By use of these linear
doi:10.7883/yoken1952.35.41
fatcat:rjhputegmvcwhdxiyh2blz6634