A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2006; you can also visit the original URL.
The file type is application/pdf
.
WT1 Activates a Glomerular-Specific Enhancer Identified from the Human Nephrin Gene
2004
Journal of the American Society of Nephrology
The glomerular filtration barrier separates the blood from the urinary space. Nephrin is a transmembrane protein that belongs to the immunoglobulin superfamily and is localized to the slit diaphragms that are a critical component of this filtration barrier. Mutations in the nephrin gene (NPHS1) lead to congenital Finnish nephropathy, whereas alterations in the level of nephrin expression have been identified in a wide range of acquired glomerular diseases. A 186-bp fragment from the human NPHS1
doi:10.1097/01.asn.0000143474.91362.c4
pmid:15504938
fatcat:zlapqkmi7rhfthxemy7ilngjh4