CM&R 2008 : 3/4 (December) 132 HMORN 2008 -Poster Presentations served as the data coordinating and analysis center (DCC). Sites obtained Institutional Review Board (IRB) approval. The VDW tables accessed included Tumor Registry, HMO Enrollment, Diagnoses, and Pharmacy. The CRN study programmer wrote SAS programs for identification of cancer cases, covariates, and stroke outcomes. The VDW programs were beta tested by a second study site. After testing, the programs were provided to the

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... two sites for data retrieval. The programs transformed the data into an entirely de-identified dataset by calculating cancer diagnosis date and all other dates to 'age in days'. The resulting data files were transferred to the DCC using the CRN secure file transfer protocol. Results: Four different levels of IRB approval were necessary across the five sites, indicating local differences in interpretation of human subjects' requirements. The VDW program development period at the lead programming site required two months, after which data were available. Beta testing took two days to complete. The third site, which ran as a 'plug and play' after beta testing worked out some additional issues requiring slight program modifications. The time from posting the final VDW program to upload of study data took less than one week for the two sites with mature VDW structures. The fourth site delivered data within three months. Preliminary analyses were generated within one month. Conclusions: Using the VDW provided efficiency for labor, cost, and time. Such studies increase the overall value of the VDW as the skills of users improves. Abstract PS1-09 Abstract PS1-10 Impact of Pre-incentives on a Web-Based Follow-Up Survey