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Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer
2019
BMC Cancer
Patients with lymph node metastasis-negative (pN0) invasive breast cancer have favorable outcomes following initial treatment. However, false negatives which occur during routine histologic examination of lymph nodes are reported to underestimate the clinical stage of disease. To identify a high-risk group in pN0 invasive breast cancer, we examined copy number alterations (CNAs) of 800 cancer-related genes. Methods: Using array-based comparative genomic hybridization (CGH) in 51 pN0 cases (19
doi:10.1186/s12885-019-5737-7
fatcat:akp7edefcbhj3ldsrrc333diz4