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Combining Results of Multiple Search Engines in Proteomics
2013
Molecular & Cellular Proteomics
A crucial component of the analysis of shotgun proteomics datasets is the search engine, an algorithm that attempts to identify the peptide sequence from the parent molecular ion that produced each fragment ion spectrum in the dataset. There are many different search engines, both commercial and open source, each employing a somewhat different technique for spectrum identification. The set of high-scoring peptide-spectrum matches for a defined set of input spectra differs markedly among the
doi:10.1074/mcp.r113.027797
pmid:23720762
pmcid:PMC3769318
fatcat:gy2w7aqv2bhdlfn7fcztdkvy2e