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An advanced, simple to use, detrending method to be used before heart rate variability analysis (HRV) is presented. The method is based on smoothness priors approach and operates like a time-varying FIR high pass filter. The effect of the detrending on time and frequency domain analysis of HRV is studied.doi:10.1109/10.979357 pmid:12066885 fatcat:hcn7xragjnan7kwoiiraw4yaxe