Effect of Dual Blockade of Renin-Angiotensin System on Proteinuria

Eqerem Hasani, Alma Idrizi, Myftar Barbullushi
2013 Open Access Macedonian Journal of Medical Sciences  
Aim: Aim of the study was the evaluation of the effect of dual blockade of the renin-angiotensin system (RAS) on proteinuria. Material and Methods: Sixty patients, included in the study, were treated with angiotensin-converting enzyme inhibitor and angiotensin receptor blocker for a period of 3 months. Results: The dual blockade of RAS resulted with decrease of proteinuria, a slight increase of serum creatinine and was not associated with a lowering of blood pressure.Conclusion: Combined
more » ... on: Combined therapy with ACE-I and ARB results in a more complete blockade of the RAS than monotherapy. In proteinuric nephropathies it reduces significantly baseline proteinuria.
doi:10.3889/oamjms.2013.004 fatcat:eyxrii432vflleefa7l65kvpvq