Enantioselectivity of some lipases: Control and prediction

Karl Hult, T. Norin
1992 Pure and Applied Chemistry  
Different strategies for the resolution of racemates in lipase catalyzed hydrolyses, esterifications, and transesterifications are presented. The importance of the equilibrium conversion for the optimization of the enantiomeric excess is emphasized. Investigations have been carried out on esters of 1-phenylethanol and 2methylalkanoic acids. Results are presented, which provide general information about important parameters for the enhancement of the enantiomeric excess and the reaction rates.
more » ... e application of a 'matched strategy' stereochemical control for
doi:10.1351/pac199264081129 fatcat:qitg5hqo6refvm4yxwsdkzgqlq