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Objectives Human parvovirus B19, the cause of fifth disease in children and transient arthropathy in adults, could induce autoimmunity and the production of autoantibodies. The aim of this study is to explore the relationship between B19 infection and autoantibodies upregulation in women and children. Methods Of 512 women and children in our hospital between 2016 and 2018, all cases simultaneously test anti-B19 IgM and autoantibodies like anti-nuclear antibody, anti-Sm and anti-double strandeddoi:10.1515/labmed-2020-0120 fatcat:bm4nlhy7mvdnxm7eh5ym3dqudu