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We compared the overall usage of veterinary therapeutic antimicrobials in Japan to the proportion of antimicrobial-resistant. Escherichia coli isolated from the feces of apparently healthy food-producing animals in 2001. The annual sales volume of veterinary antimicrobials, which is published and accumulated information, was subdivided according to the target animal species (cattle, pigs, broiler chickens, and layer chickens). The antimicrobial susceptibility of the isolates was examinedpmid:16377870 fatcat:yv63rqwk5fhcpd5opfwgpdtxbi