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Bursal lymphocyte proliferation in the presence of phorbol myristate acetate: Effect of IBDV strains on the proliferation response
1999
Avian Pathology
Preserved Fulltext
Phorbol myristate acetate (PMA) was shown to be highly mitogenic for bursal lymphocytes (optimal concentration 2 m g/ml). Groups of 1-day-old chickens were inoculated with infectious bursal disease virus (IBDV, vaccine or virulent strains). Seven days after infection bursae were removed and the proliferation response of the bursal lymphocytes to PMA was determined. A signi® cant reduction in the proliferation response was observed in the IBDV-inoculated birds. The results con® rm that PMA is
doi:10.1080/03079459994795
pmid:26915386
fatcat:wpsy6z6sznalpl65tyfebnnice