Cycloartenyl Ferulate and β-Sitosteryl Ferulate - Steryl Ferulates of γ-Oryzanol - Suppress Intracellular Reactive Oxygen Species in Cell-based System

Shusuke Yasuda, Yoshihiro Sowa, Hiroyuki Hashimoto, Takuya Nakagami, Takuo Tsuno, Toshiyuki Sakai
2019 Journal of Oleo Science  
γ-Oryzanol is a naturally occurring component of rice bran and consists of various steryl ferulates. The antioxidant activities of γ-oryzanol have mostly been demonstrated in cell-free systems. Therefore, we determined whether steryl ferulate of γ-oryzanol suppress spontaneous intracellular reactive oxygen species (ROS) in cell-based systems. We found that cycloartenyl ferulate and β-sitosteryl ferulate suppressed spontaneous intracellular ROS in a similar way to N-acetylcysteine and α-tocopherol.
doi:10.5650/jos.ess19054 pmid:31292340 fatcat:oduca5hs7jcclhorkjckbasaxq