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Large-scale production of Extracellular Vesicles: report on the "massivEVs" ISEV workshop [report]

Lucia Paolini, Marta Monguió-Tortajada, Marta Costa, Fabio Antenucci, Mario Barilani, Marta Clos-Sansalvador, André Cronemberger Andrade, Tom A.P. Driedonks, Sara Giancaterino, Stephanie M. Kronstadt, Rachel R. Mizenko, Muhammad Nawaz (+21 others)
2022 Zenodo  

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Extracellular vesicles large-scale production is a crucial point for the translation of EVs from discovery to application of EV-based products. In October 2021, the International Society for Extracellular Vesicles (ISEV), along with support by the FET-OPEN projects, evFOUNDRY and VES4US, organized a workshop entitled "massivEVs" to discuss the potential challenges for translation of EV-based products. This report gives an overview of the topics discussed during "massivEVs", the most important
more » ... ints raised, and the points of consensus reached after active discussion among academia and industry representatives. Overall, the review of the existing EV manufacturing and upscaling challenges and the directions for their resolution highlighted in the workshop was constructive and painted an optimistic future for the dynamically expanding EV field.
doi:10.5281/zenodo.6594977 fatcat:qjbm4skkqnbslgzkneuxkjoada
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Lucia Paolini, Marta Monguió-Tortajada, Marta Costa, Fabio Antenucci, Mario Barilani, Marta Clos-Sansalvador, André Cronemberger Andrade, Tom A.P. Driedonks, Sara Giancaterino, Stephanie M. Kronstadt, Rachel R. Mizenko, Muhammad Nawaz, Xabier Osteikoetxea, Carla Pereira, Surya Shrivastava, Anders Toftegaard Boysen, Simonides Immanuel van de Wakker, Van Herwijnen, Xiaoqin Wang, Dionysios C. Watson, Mario Gimona, Maria Kaparakis-Liaskos, Konstantin Konstantinov, Sai Kiang Lim, Nicole Meisner-Kober, Michiel Stork, Peter Nejsum, Annalisa Radeghieri, Eva Rohde, Nicolas Touzet, Marca H. M. Wauben, Antonella Bongiovanni, Paolo Bergese. "Large-scale production of Extracellular Vesicles: report on the "massivEVs" ISEV workshop." Zenodo (2022)