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The rapid analysis of human serum and plasma can provide deep insights into changes of the blood proteome in response to different patient treatments or diseases. Targeted proteomics techniques, like SRM and PRM, can be utilized to monitor proteins at high sensitivity, but so far were limited to smaller protein panels, which can be monitored in one experiment. The recently, on a Bruker tims-TOF Pro mass spectrometer, developed parallel reaction monitoring-parallel accumulation−serialdoi:10.1101/2022.04.01.486663 fatcat:ax22qyonxvdnvchrvdazxjhxea