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Molecular characterization of hepatitis A virus isolates from Goiânia, Goiás, Brazil
2008
Memórias do Instituto Oswaldo Cruz
Hepatitis A virus (HAV) infection is a public health problem worldwide and the virus has been classified into six genotypes. In Brazil, the only genotype that has been found is genotype I, predominately from subgenotype IA. Here, the HAV genotypes were analyzed of 18 isolates circulating between 1996-2001 in Goiânia, state of Goiás, Brazil. Viral RNA was extracted from 18 serum samples and amplified (RT-PCR/nested-PCR), followed by the genomic sequencing of the VP1/2A junction region of the HAV
doi:10.1590/s0074-02762008000800015
pmid:19148425
fatcat:sb7dx4ckrnelzatbmpgz75pfse