Whole brain segmentation with full volume neural network

Yeshu Li, Jonathan Cui, Yilun Sheng, Xiao Liang, Jingdong Wang, Eric I-Chao Chang, Yan Xu
2021 Computerized Medical Imaging and Graphics  
Whole brain segmentation is an important neuroimaging task that segments the whole brain volume into anatomically labeled regions-of-interest. Convolutional neural networks have demonstrated good performance in this task. Existing solutions, usually segment the brain image by classifying the voxels, or labeling the slices or the sub-volumes separately. Their representation learning is based on parts of the whole volume whereas their labeling result is produced by aggregation of partial
more » ... ion. Learning and inference with incomplete information could lead to sub-optimal final segmentation result. To address these issues, we propose to adopt a full volume framework, which feeds the full volume brain image into the segmentation network and directly outputs the segmentation result for the whole brain volume. The framework makes use of complete information in each volume and can be implemented easily. An effective instance in this framework is given subsequently. We adopt the 3D high-resolution network (HRNet) for learning spatially fine-grained representations and the mixed precision training scheme for memory-efficient training. Extensive experiment results on a publicly available 3D MRI brain dataset show that our proposed model advances the state-of-the-art methods in terms of segmentation performance.
doi:10.1016/j.compmedimag.2021.101991 pmid:34634548 fatcat:c4wq6dnmxvfyllgmkra7j3dg3i