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Human Brain Mapping
There are a wealth of tools for fitting linear models at each location in the brain in neuroimaging analysis, and a wealth of genetic tools for estimating heritability for a small number of phenotypes. But there remains a need for computationally efficient neuroimaging genetic tools that can conduct analyses at the brain-wide scale. Here we present a simple method for heritability estimation on twins that replaces a variance component model-which requires iterative optimisation-with adoi:10.1002/hbm.24611 pmid:31037793 pmcid:PMC6680147 fatcat:dyyqidmvk5dkfgxbl5weqnzwuu