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In SilicoEvolution of Gene Cooption in Pattern-Forming Gene Networks
2012
The Scientific World Journal
Gene recruitment or cooption occurs when a gene, which may be part of an existing gene regulatory network (GRN), comes under the control of a new regulatory system. Such re-arrangement of pre-existing networks is likely more common for increasing genomic complexity than the creation of new genes. Using evolutionary computations (EC), we investigate how cooption affects the evolvability, outgrowth and robustness of GRNs. We use a data-driven model of insect segmentation, for the fruit fly
doi:10.1100/2012/560101
pmid:23365523
pmcid:PMC3540831
fatcat:ebc677suwjh6zfvlive6euf6du