Preparation and evaluation of prednisolone sodium phosphate ocusert for controlled drug delivery

Karan Sharma, Navneet Nagpal
2018 Journal of Pharmaceutical and BioSciences  
The intent of research was to formulate and evaluate controlled release drug delivery system of ocusert of prednisolone sodium phosphate, corticosteroid for the treatment of viral conjunctivitis. Ocusert are sterile preparation having drug as dispersion or as solution in the polymeric base. Ocusert were formulated using different polymers such as hydroxypropyl methyl cellulose E-15, ethyl cellulose, and Eudragit RL-100 at various concentrations and combinations. Films were prepared by mercury
more » ... sting method using different ratios of polymers. Selected physiochemical properties such as thickness, weight, percentage moisture absorption, and in-vitro release pattern of Prednisolone sodium phosphate ocusert were studied and reported.
doi:10.31555/jpbs/2018/6/1/5-8 fatcat:3wv4sfdyajbcdjemvlkyycejl4