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Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
[article]
2019
bioRxiv
pre-print
Reiterative transcription is a non-canonical form of RNA synthesis by RNA polymerase in which a ribonucleotide specified by a single base in the DNA template is repetitively added to the nascent RNA transcript. We previously determined the X-ray crystal structure of the bacterial RNA polymerase engaged in reiterative transcription from the pyrG promoter, which contains 8 poly-G RNA bases synthesized using 3 C bases in the DNA as a template and extends RNA without displacement of the promoter
doi:10.1101/732214
fatcat:76afmwk2mbgyvaq3gszhq7anbi