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Adaptation des tRNA et optimisation de la traduction
1981
Reproduction nutrition development (Print)
tRNA adaptation in optimizing translation. The intracellular level of each tRNA species is adjusted to the codon frequency of the mRNA being decoded. This was first observed in such hi'ghly differentiated cells as the silk gland of Bombyx mori, which produces fibroin and sericin, and the rabbit reticulocyte. tRNA adaptation also occurs in other cell types from E. coli to mammalian cells. Regardless of the mechanism regulating tRNA biosynthesis, we believe that tRNA adaptation is the basic step
doi:10.1051/rnd:19810202
fatcat:3t22f7rl7feazmhwdsbj3djeoa