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Tetrahydrofuran amino acid-containing gramicidin S analogues with improved biological profiles
2015
Organic and biomolecular chemistry
Preserved Fulltext
Replacement of the d-Phe-Pro units of GS with novel C6-Bn-substituted tetrahydrofuran amino acid minimized its cytotoxicity while preserving its antimicrobial activity, with a few analogs showing selective anti-TB activity as well.
doi:10.1039/c5ob00622h
pmid:26008215
fatcat:klbjtmom65ei5pibyod2uie45m