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The molecular basis for a temperature-sensitive Mycobacterium smegmatis glgE mutant
[article]
2020
bioRxiv
pre-print
Background- The bacterial GlgE pathway is the third known route to glycogen and is the only one present in mycobacteria. It contributes to the virulence of Mycobacterium tuberculosis. The involvement of GlgE in glycogen biosynthesis was discovered twenty years ago when the phenotype of a temperature-sensitive Mycobacterium smegmatis mutation was rescued by the glgE gene. The evidence at the time suggested glgE coded for a glucanase responsible for the hydrolysis of glycogen, in stark contrast
doi:10.1101/2020.04.23.057067
fatcat:khx76bdtcbfolaflkq2hga4ale