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Interference with Establishment of Immunologic Tolerance to Shigella Antigens in Neonatal Mice by Specific Antiserum
1965
Journal of Immunology
Administration of hyperimmune mouse anti-Shigella serum to newborn mice receiving a tolerance-inducing inoculum of Shigella soluble antigen (SSA) interferes with establishment of tolerance. An interval of 1 or 2 days between injection of antigen at birth and administration of antiserum results in only partial interference with tolerance, while an interval of several days or more results in no demonstrable effect. γ-Globulin containing fractions prepared from hyperimmune mouse serum is also
doi:10.4049/jimmunol.94.6.921
fatcat:zzmmb2guwfdzrik6aeyuvduw4y