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The undersigned certify that they have read, and recommend to the Faculty of Graduate Studies for acceptance, a thesis entitled "1α, 25-dihydroxyvitamin D 3 induced osteogenesis in murine embryonic stem cells: the role of Wnt5a" Abstract This thesis explores the role of Wnt5a during in vitro differentiation of murine embryonic stem cells to osteoblasts. It shows for the first time that Wnt5a gain of function increases mineralization, specifically calcification, during osteoblastdoi:10.11575/prism/22803 fatcat:7bnbxmw5tfa3tp22bmrevhvgee