Regional Differences of Drinking Water Iodine and Its Association with Thyroid Disorder and Serum Iodine

Jwan Jawzali
Medical Journal of Babylon   unpublished
The study aims to evaluate relationship between drinking water iodine and serum iodine with thyroid disorders in patients with symptomatic thyroid disease in Erbil province, Iraq. Outpatients attending Rizgariy and Hawler teaching hospital, Erbil province, were participated in this cross sectional study and samples of drinking water were collected randomly from different geographical region of Erbil province. Biochemical analyses included; serum thyroid hormones, serum iodine and drinking water
more » ... and drinking water iodine. Level of water and serum iodine were deficient 24.1± 6.8 μg/l (SD)μg/l and 24.4 ± 21.4 (SD) μg/l respectively. Highest level of the water iodine was in south west of Erbil city and the lowest one was in the east districts. Water iodine showed significant negative correlation with thyroid stimulating hormone (TSH) in patients with abnormal thyroid function and significant increase risk of hypothyroidism in regions with low water iodine. 20% of patient had hypothyroidism. Serum iodine didn't correlated with water iodine while there was significant negative correlation of it with TSH hormone. Deficiency of drinking water iodine reflects effect of environmental factors on water quality. It is a potential risk factor for developing thyroid disorder especially hypothyroidism in reproductive age of housewives. Continued monitoring treatment and iodized salt programs could prevent hypo and hyperthyroidism. Key Words: Water and serum iodine, Thyroid disorder, Erbil /Kurdistan / Iraq ‫الخالصة‬ ‫بيل‬ ‫ار‬ ‫محافظة‬ ‫فى‬ ‫قية‬ ‫الدر‬ ‫الغدة‬ ‫اض‬ ‫امر‬ ‫و‬ ‫الدم‬ ‫ومصل‬ ‫الشرب‬ ‫ماء‬ ‫في‬ ‫اليود‬ ‫محتوى‬ ‫بين‬ ‫العالقة‬ ‫استبيان‬ ‫الى‬ ‫اسة‬ ‫الدر‬ ‫تيدف‬ / ‫اق‬ ‫العر‬. ‫اسة‬ ‫الدر‬ ‫كانت‬ ‫رزكاري‬ ‫مستشفى‬ ‫من‬ ‫عمييا‬ ‫الحصول‬ ‫تم‬ ‫التي‬ ‫و‬ ‫قية‬ ‫الدر‬ ‫الغدة‬ ‫مرض‬ ‫اض‬ ‫اعر‬ ‫من‬ ‫يعانون‬ ‫الذين‬ ‫المرضى‬ ‫من‬ ‫الدم‬ ‫عينات‬ ‫عمى‬ ‫شممت‬ ‫و‬ ‫وصفية‬ ‫الجميو‬ ‫و‬ ‫بيل‬ ‫ار‬ ‫محافظة‬ ‫في‬ ‫ري‬ , ‫بشكل‬ ‫جمعت‬ ‫الشرب‬ ‫ماء‬ ‫من‬ ‫وعينات‬ ‫ائي‬ ‫عشو‬ ‫لممرضى‬ ‫مختمفة‬ ‫مناطق‬ ‫لتغطية‬ ‫البيوت‬ ‫من‬ ‫في‬ ‫لغرض‬ ‫بيل‬ ‫ار‬ ‫محافظة‬ ‫قية‬ ‫الدر‬ ‫الغدة‬ ‫ىورمونات‬ ‫ومستوى‬ ‫الشرب‬ ‫وماء‬ ‫الدم‬ ‫في‬ ‫اليود‬ ‫مستوى‬ ‫تحميل‬. ‫الشرب‬ ‫وماء‬ ‫الدم‬ ‫في‬ ‫اليود‬ ‫محتوى‬ ‫فى‬ ‫نقص‬ ‫اسة‬ ‫الدر‬ ‫نتائج‬ ‫اظيرت‬ , ‫وكانت‬ g/l μ 24.4 ± 21.4 ‫و‬ 24.1± 6.8 μg/l ‫الي‬ ‫التو‬ ‫عمى‬ , ‫مدينة‬ ‫قي‬ ‫شر‬ ‫جنوب‬ ‫منطقة‬ ‫في‬ ‫كان‬ ‫الشرب‬ ‫ماء‬ ‫في‬ ‫لميود‬ ‫مستوى‬ ‫اعمى‬ ‫بان‬ ‫وتبين‬ ‫بيل‬ ‫ار‬ , ‫المدينة‬ ‫خارج‬ ‫بية‬ ‫الغر‬ ‫مناطق‬ ‫في‬ ‫كان‬ ‫مستوى‬ ‫اقل‬ ‫و‬. ‫بان‬ ‫التحاليل‬ ‫اظيرت‬ ‫و‬ 20 % ‫قية‬ ‫الدر‬ ‫الغدة‬ ‫نشاط‬ ‫فى‬ ‫خمول‬ ‫ليم‬ ‫المرضى‬ ‫من‬. ‫بينت‬ ‫اإلحصا‬ ‫التحميل‬ ‫نتائج‬ ‫عكسية‬ ‫معنوية‬ ‫عالقة‬ ‫وجود‬ ‫عمى‬ ‫ئي‬ ‫بين‬ ‫ما‬ ‫قية‬ ‫الدر‬ ‫محفز‬ ‫ىورمون‬ ((TSH ‫و‬ ‫الشرب‬ ‫ماء‬ ‫في‬ ‫اليود‬ ‫ومستوى‬ ‫الدم‬. ‫النتائج‬ ‫ودلت‬ ‫ومعال‬ ‫قية‬ ‫الدر‬ ‫الغدة‬ ‫اض‬ ‫امر‬ ‫مع‬ ‫وثيقة‬ ‫عالقة‬ ‫لو‬ ‫الذي‬ ‫اليود‬ ‫محتوى‬ ‫عمى‬ ‫وبالتالي‬ ‫الشرب‬ ‫مياه‬ ‫نوعية‬ ‫عمى‬ ‫ثر‬ َ ‫تو‬ ‫البيئية‬ ‫امل‬ ‫العو‬ ‫بان‬ ‫ايضا‬ ‫جتيا‬ ‫مح‬ ‫عمى‬ ‫انعكاسيا‬ ‫و‬ ‫اليود‬ ‫توى‬ ‫في‬ ‫الدم‬. ‫مستمر‬ ‫بشكل‬ ‫و‬ ‫بدقة‬ ‫اليود‬ ‫نقص‬ ‫عالج‬ ‫نامج‬ ‫بر‬ ‫متابعة‬ ‫اىمية‬ ‫عمى‬ ‫ايضا‬ ‫النتائج‬ ‫كد‬ َ ‫وتو‬ .
fatcat:slpfkbdlcvectmrkqtoplsoph4