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Release Control of Prednisolone from Suppository Prepared Using Powder of Pulverized Tablet
Prednisolone suppositories have been used successfully for the treatment of ulcerative colitis in hospital settings. However, the raw material of prednisolone suppository, JP prednisolone powder (JP Powder), was recently removed from the market. Therefore we studied the eŠects of raw material and suppository base on the release of prednisolone suppository for the purpose of designing a new suppository with similar eŠects to those of suppository prepared using JP powder (old suppository). Newdoi:10.1248/yakushi.128.641 pmid:18379182 fatcat:6hjvdnxxrfdt7pjit5kpqht5i4