ORIGINAL ARTICLES Molecular Modeling and Spectroscopic Analyses Study of Flutamide 1

Abdel Mahmoud, Abdel Mahmoud, Nahla Elkashef, Ihab Elkashef
2012 Journal of Applied Sciences Research   unpublished
Flutamide is an important drug for the advanced treatment of prostate cancer. Some researchers reports against this drug as it has some adverse effects. Accordingly semiemperical PM3 quantum mechanical method has been utilized to study this important drug. The aim is to pave the way towards maximizing the benefits and minimize the side effects of this drug. Some physical as well as thermodynamical parameters are presented together with the vibrational assignments for the flutamide.