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Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice
2016
American Journal of Physiology. Endocrinology and Metabolism
gence of thermogenic adipocytes such as brown and beige adipocytes is critical for whole body energy metabolism. Promoting the emergence of these adipocytes, which increase energy expenditure, could be a viable strategy in treating obesity and its related diseases. However, little is known regarding the mechanisms that regulate the emergence of these adipocytes in obese adipose tissue. Here, we demonstrated that classically activated macrophages (M1 M) suppress the induction of thermogenic
doi:10.1152/ajpendo.00028.2015
pmid:26884382
fatcat:6rokblcg7vhvlmkp6l3puobgtq