Comparative Detection of Processed Small RNAs in Archaea

Christian Höner zu Siederdissen, Sarah Berkemer, Fabian Amman, Axel Wintsche, Sebastian Will, Sonja J. Prohaska, Peter F. Stadler
2014 International Work-Conference on Bioinformatics and Biomedical Engineering  
Enzymatic splicing in Archaeal tRNAs is guided by bulgehelix-bulge structural elements, while much less seems to be known about splicing in other small RNAs (sRNAs). We conduct a genome-wide analysis of several archaeal genomes to identify putative BHB elements and compare our findings with available RNA-seq data. We also provide an analysis of the viability of using pattern-based and stochastic structural scanning algorithms for in silico studies of the occurrence of BHB motifs. Furthermore,
more » ... comment on splicing motifs in other small RNAs, which mostly do not fit the pattern of bulge-helix-bulge motifs.
dblp:conf/iwbbio/SiederdissenBAW14 fatcat:xzvswf4hkvbubakk3j3qpok7cm