Separation/Analysis of Chrysophanol by Ionic Liquid Loaded β-Cyclodextrin Polymer Coupled with Ultraviolet Spectrophotometry

Xiashi Zhu
2012 Biochemistry & Analytical Biochemistry  
A novel method for separation/analysis of chrysophanol (Chry) in drugs is described. The work is based on the utilization of ionic liquid ([C4min] PF6) (IL) loaded β-cyclodextrin cross-linked polymer (IL-β-CDCP) for effective adsorption of Chry coupled with ultraviolet spectrophotometry for the analysis of Chry. The inclusion interaction of IL-β-CDCP with Chry is studied by FTIR and 13 C-NMR. Under the optimum conditions, linear range, Detection Limit (DL) and the relative standard deviation
more » ... 0.10-20.0 μg mL -1 , 0.02 μg mL -1 , 0.45% (n=3, c=4.0 μg mL -1 ), respectively. This technique is successfully applied for determination of Chry in drug samples.
doi:10.4172/2161-1009.1000138 fatcat:5ez7enbvnfbblgoap5sbqg57zm