In order to overcome the 21st century's challenges such as national energy supply security, global warming, and resource depletion, we are struggling to accelerate the paradigm shift in our life style from fossil fuel-based economy to biomass-based economy. In the context of sustainable bioeconomy revitalization, we comprehensively review the development status of the biorefinery as a system for bioenergy/biochemicals co-products on the basis of the various categories according to six criteria.