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Evidence of cerebrovascular disease at autopsy was compared in 2 groups of men: 186 longtime residents of Hiroshima, Japan, and 253 men of Japanese ancestry long resident in Honolulu, Hawaii. They were 45 to 71 years-of-age at death. Atherosclerosis of the circle of Willis and its major branches, sclerosis of the intraparenchymal arteries and the frequency of cerebral hemorrhage and cerebral infarct were compared in the 2 populations. The Honolulu subjects had significantly more atherosclerosisdoi:10.1161/01.str.10.4.389 pmid:505476 fatcat:xfiygqlm3jdvhaes6ikjm5q7iq