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Calcium, phosphorous, fluoride, and Vitamin D principally take part in the development of hard tissues of the body -the bone and the tooth structure and we have named them as EFC. Calcium is of utmost importance among these factors and accounts for about 40% of the total body mineral and 99%, of which is found in the skeleton. Most of the mineral exist in the form of hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 ). Calcium is regulated by various hormones suchdoi:10.21276/apjhs.2018.5.1.9 fatcat:njvjr2kqojccrlgo4ascvcxbby