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CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure
2019
BMC Cancer
Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with a patients' asbestos exposure. However, the status of CDKN2A and the expression of the corresponding protein, p16, in relation to MPM patient's asbestos exposure is poorly known. Copy number alterations in 2p16, 9q33.1 and 19p13 have earlier been shown to accumulate in
doi:10.1186/s12885-019-5652-y
pmid:31138176
pmcid:PMC6537412
fatcat:vqcgs7p36fbzdm7zc2fh2tafya