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DEDICATION I dedicate this dissertation to my fiance, Mckenzie, who has supported me through my graduate research and has always been a good listener when experiments didn't work. This dissertation is also dedicated to my parents, who have always encouraged me to dream big and work hard, and to my brother and sister who have inspired me to be a good role model and who were always willing to make time to enjoy activities together. iv ACKNOWLEDGEMENTS I would like to thank my graduate researchdoi:10.21007/etd.cghs.2013.0088 fatcat:u7dt525x2jgtji2fbn3flkgcsm